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Biotage

> Microwave Organic Synthesis
> Flash Chromatography
> Solvent Evaporation
> Process Development
> Analytical Chemistry / Solid Phase Extraction


Microwave Organic Synthesis
Initiator 2.0
Initiator 2.0 is the easiest, safest and most powerful microwave synthesizer available. A more powerful 400 watt magnetron delivers the most precise heating control of any microwave synthesis instrument on the market. A new USB port enables chemists to share or store methods and results via memory stick or remote network connection. Built-in computer and touch-screen interface eliminate the additional cost and hassle of an external computer. New software includes a wizard that guides users and automatically converts conventional parameters to microwave conditions. Easily upgrade from a single-sample manual format to an automated 60-position system.
Initiator™ Eight
The safe, multi-user microwave synthesizer that supports automated method development, analog and multi-gram synthesis. The 8-position sample bed provides automation to medicinal chemists for rapid optimization of reaction conditions and analog synthesis. The ability to use both large and small vials provides the medicinal chemist flexibility and the ability to rapidly scale-up compounds of interest.
Initiator™ Sixty
Synthesize compounds FASTER and EASIER using microwave heating. The 60-position sample bed supports the production of focused libraries, multi-user environments, and scale-out. Flexible operation enables the use of both large and small vials in combination at any time and in any order without manual intervention.
Note: Products listed are subject to change without notice and availability may vary from country to country.
 

Flash Chromatography
SP1™ Purification System
The single-column flash purification system with Touch Logic Control™ and TLC-to-gradient feature designed to accelerate and simplify the purification process. SP1’s compact footprint fits easily into a standard fume hood. Built-in, computerized control operates the system with the power of a full PC, without requiring additional lab-space for an external computer, keyboard or mouse
SP4™ Purification System
SP4 EXP—four-column sequential FLASH purification system with expanded fraction bed, designed for multi-sample purification. SP4 systems accommodate the broadest range of cartridge sizes on a single system (FLASH 12™+S [4.5g silica] through FLASH 75™L [800g silica]). Automatically purify milligrams of final compound or tens of grams of an intermediate while running your next synthesis
FlashMaster™ II
The FlashMaster II system is a space-saving and cost-effective solution for groups of chemists that must adopt automated purification methods in order to purify more compounds in less time. Ten readily accessible column positions allow chemists to queue their own samples for purification without interrupting a separation already in progress. Separate system user profiles, unambiguous fraction identification, and e-mail notification of run completion make the FlashMaster II system an ideal shared resource that costs far less, and requires less lab space than any combination of individual systems with equivalent throughput
Note: Products listed are subject to change without notice and availability may vary from country to country.
 

Solvent Evaporation
V-10 Evaporator
The Biotage V-10 solvent evaporation system rapidly dries samples dissolved in both aqueous and organic solvents up to 20x faster than traditional rotary or centrifugal evaporators, leaving solvent-free product in the vial. This innovative vortex and vacuum evaporation technology was developed through collaboration with major pharmaceutical companies.
Note: Products listed are subject to change without notice and availability may vary from country to country.
 

Process Development
Atlantis Pressure Reactor System
The Atlantis pressure scale-up workstation performs and optimizes gas/liq and gas/liq/solid, heterogeneous reactions with the unique ability to monitor live gas consumption. Process Chemists can easily load experiments with push-button hardware and precisely control and monitor reactions with simple-to-use software.
Advantage Series® 2410
Personal Screening Synthesizer

The 2410 personal screening synthesizer is designed to help process chemists who work with small amounts of material, simulate and replicate the thermal and mixing conditions seen in larger production reactors.
Advantage Series® 3400
Process Chemistry Workstation

The Advantage Series® 3400 process chemistry workstation is a modular, multi-reactor system designed to automate chemical process development. The Advantage Series® 3400 workstation automatically captures and documents process chemistry workflow.
Advantage Series® 4100 Process Scale-up Reactor
Developed with the chemist in mind, the Advantage Series 4100 process scale-up reactor provides improved experimentation control while allowing the process chemist to quickly study results and plan for the next experiment.

- Saves hours of hands-on time
- Uses real-time feedback from analytics interfaces
- Controls multiple reaction parameters from one interface

Biotage Advancer
Specifically designed so that methods developed in Biotage lab-scale systems can be safely and predictably transferred to a larger scale without re-optimization. Powerful mechanical stirring (up to 1000 rpm) In addition to homogeneous reactions, the system also supports heterogeneous reactions and the use of solid catalysts, heavy slurries and crystallizing products.
Endeavor® Catalyst Screening System
The Endeavor Catalyst Screening System is a parallel, multi-reactor synthesizer that is the fastest, most effective and simplest way to optimize pressurized reactions. The Endeavor system uses parallel reactors and automated control of pressurization, heating and mixing to provide rapid assessment of a variety of reaction conditions to dramatically increase productivity.
Note: Products listed are subject to change without notice and availability may vary from country to country.
 

Analytical Chemistry / Solid Phase Extraction
VacMaster®-96 Sample Processing Manifold
The VacMaster-96 sample processing manifold has been designed with the needs of the bioanalytical scientist in mind. This manifold is ideal when processing 96-well SPE, supported liquid extraction or protein precipitation plates either manually or with an automated liquid handling system. The robust, inert construction materials make it easy to clean - particularly important for biological fluid applications.
ISOLUTE® SPE Products
ISOLUTE® SPE products are a range of leading quality SPE columns and 96-well plates, packed with a variety of ISOLUTE non-polar, mixed-mode and ion exchange sorbents.
EVOLUTE™ Sample Preparation Products
EVOLUTE™ Sample Preparation Products are advanced water-wettable polymer-based sorbents for extracting drugs from biological fluids. Developed specifically for analyte quantification by LC-MS/MS, EVOLUTE products provide a highly effective solution to the problems of ion suppression and matrix effects from dirty extracts.
ISOLUTE® SLE+ Supported Liquid Extraction Plates
Supported Liquid Extraction (SLE) provides an easier to automate alternative to liquid-liquid extraction (LLE), with no off-line steps (e.g. mixing or centrifuging) required. Problems including emulsion formation, and separation of liquid layers are eliminated.

ISOLUTE® SLE+ Supported Liquid Extraction Plates are optimized for simultaneous processing of 96 samples (extract up to 200 µL of plasma or urine per well), using a generic methodology for extraction of neutral, acidic and basic compounds.

Note: Products listed are subject to change without notice and availability may vary from country to country.
 

 
 
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