Preparative HPLC System
The systems's wide flow rate range (from the 333 and 334 Pumps) allows for both semi-preparative and preparative separations. High pumping power accommodates a wide range of preparative column sizes. All injection modules feature a continuous flow path design. The system can accommodate large injection volumes with minimal sample waste and carryover. The new rinse station system incorporates a flowing jet wash and allows the use of up to two different rinse solvents.

Semi-preparative to Preparative HPLC System
Gilson's Semi-preparative to Preparative HPLC Systems deliver high performance for scale-up to large-scale HPLC on the same system.

Analytical to Semi-preparative HPLC System
Gilson's Analytical to Semi-preparative HPLC Systems are your complete solution for automated HPLC purification and analysis of synthesized compounds. The versatile system performs sample injection, fraction collection and re-injection of collected fractions.

845ZPREP™ System
Gilson’s new 845ZPREP™ System features Gilson’s innovative injection technique of the 845Z Injection Module paired with the new RV 700-112 valve. The RV 700-112 valve’s large 0.040" ID ports accommodate flow rates up to 150 mL/min for semiprep to prep applications. The fast injection switching time of <200 ms provides optimal injection results by preventing pressure spikes from the valve switching. The novel approach to injection of the 845ZPREP™ Injection Module moves the injection valve to the sample; sample is aspirated directly into the injection valve, removing the need for an injection port. This technique provides decreased maintenance, faster injection cycle times and allows collection of early-eluting peaks, while reducing carryover.

When paired with the Low-Mount Fraction Collection Valve, the 845ZPREP System provides separate injection and fraction collection fluid paths, eliminating contamination of fractions from the injection process. The 845ZPREP System is an ideal choice for semipreparative to preparative injection and fraction collection providing fast, low carryover purification capabilities.

cLC™ System
Gilson’s cLC System is a complete chromatography system capable of automating the purification of compounds using both normal-phase and reverse-phase columns. The cLC System also has the ability to accommodate various detection modes including UV/Vis, ELSD, MS or RI. Additional analytical components are also integrated into the cLC System, enabling automated on-line evaluation of the collected fractions for purity and recovery.

Multiple Probe 215 System
The Multiple Probe 215 System delivers high-throughput injection for analysis onto HPLC or LC/MS.

SPE 215 System
The optimal solution for high throughput solid phase extraction and sample purification. The SPE 215 System provides versatile application support accommodating 96-well extraction plates, 1 mL and 3 mL SPE cartridges. Positive Pressure elution through Gilson's integrated Sealing Foot design increases accuracy and liquid transfer precision.

GX-271 ASPEC™
Whether your application is pharmaceutical, clinical, forensic, or environmental, SPE has become the technique of choice for sample cleanup, sample prep, and trace analyte enrichment due to its inherent versatility, selectivity, speed and low solvent usage. Designed with today’s laboratory in mind, the GX-271 ASPEC™ has large cartridge capacity while minimizing its linear bench space footprint. System pressure is constantly monitored by a pressure sensing module to provide error handling for over pressurization as well as to monitor real-time cartridge pressures. Carryover and cross-contamination concerns are minimized with the use of Gilson’s revolutionary jet wash rinse stations. The GX-271 ASPEC combines the throughput and reliability to run unattended making this instrument an ideal choice for SPE, sample prep, sample clean up and GPC / SPE applications.

GX-274 ASPEC™
Maximize efficiency and throughput with the unattended, parallel solid phase extraction processing of samples via Gilson’s GX-274 ASPEC™. It’s as easy as placing your samples on the instrument, inserting SPE cartridges in the mobile racks, and filling solvent reservoirs. Then, create your sample list with the powerful TRILUTION® LH software and press start...it’s that easy. The GX-274 ASPEC is a higher throughput four-probe instrument capable of processing up to 4 samples in parallel to increase both throughput and the efficiency of your cartridge-based applications. Based on positive pressure elution, this instrument processes up to four samples in a single step with an innovative and proven sealing cap technology, where each cartridge is sealed, run, and monitored individually. The two 406 Dual Syringe Pumps allow the user to transfer liquids, process up to four samples in parallel, and to monitor pressure on each fluid path individually.

Automated GX-271 GPC Clean-up System
Automate post-extraction clean-up of interfering substances from environmental samples, food products and animal tissue by Gel Permeation Chromatography (GPC) prior to analysis by GC, GC/MS, HPLC or LC/MS. Failure to remove these interfering compounds can cause poor analytical results, shorten column life and increase analytical downtime.

The Automated GX-271 GPC Clean-up System provides an affordable solution for laboratories performing residue analysis of complex matrices such as fatty foods, soils, sludge, animal and plant tissue.

• The system features a Direct Injection Module and a fraction collection valve located on the Z-arm, increasing efficiency by reducing sample carryover and post valve dead volume.

• The Automated GPC system is controlled with TRILUTION® LC Software, a user-friendly, easy-to-use, flexible program that was specifically designed to meet the laboratory needs. The software features pre-programmed methods specific to GPC post-extraction clean-up processes.

• Gilson GPC Clean-up Systems meet clean-up guidelines set forth by the USEPA, USFDA, USDA, USGS, ISO, CFIA, AOAC International and European Union (EN 1528, EN 12393, S19) requirements.

Manual GPC Clean-up System
Gilson’s Manual GPC Clean-up System is a simple and economical solution within a small footprint requiring minimal bench space. Gel permeation chromatography (GPC) clean-up systems are an ideal solution for post-extraction clean-up of interfering substances from environmental samples, food products and animal tissue, prior to analysis by GC, GC/MS, HPLC or LC/MS. Failure to remove these interfering compounds can cause poor analytical results, shorten column life and increase analytical downtime.

• Bench space-efficient system incorporating a stackable modular design.
• System coordinates the elution and collection to user-defined parameters.
• Ideal for small sample load requirements.
• Semi-automate clean-up processes by automatically collecting multiple fractions by time windows that are pre-programmed through Gilson’s mobile phase 307 Pump keypad.
• Gilson GPC Clean-up Systems meet clean-up guidelines set forth by the USEPA, USFDA, USDA, USGS, ISO, CFIA, AOAC International and European Union (EN 1528, EN 12393, S19) requirements.

Gilson, Inc., inventor of the Pipetman® and the leader in the manual pipetting market, has incorporated its vast knowledge of liquid transfer techniques into a wide range of automated liquid handlers. Our instruments take the guesswork out of repetitive liquid handling tasks through software-controlled automation. The entire array of automated liquid handlers can be optimized for assays via task-oriented software and customizable deck layouts. This incredible flexibility exists throughout the entire automated Liquid Handling family. From robust instruments for reformatting techniques to complicated assay procedures with disposable tip or fixed probe options, Gilson has an automated solution to meet your liquid handling application requirements.